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An online medical and health information center on allergy, allergy symptoms, allergy relief, asthma, asthma attack, sinusitis, sinus problems, sinusitis symptoms, plus mold health problems and more mold information for residents of the USA, Canada, Mexico, the Caribbean, Central America, South America, Asia, Australia, New Zealand, Africa, the Middle East, and Europe.

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Getting Relief from Allergies: How Allergies Work

The immune system protects the body from harmful substances: white blood cells target viruses, bacteria and other threats, producing antibodies that destroy the invading threat. An allergic reaction occurs when the body's immune system overreacts to otherwise harmless substances.

The body can usually differentiate between dangerous invaders and benign substances. An overly sensitive immune system, however, mistakes non-threatening substances for more harmful invaders, and attempts to destroy them. The resulting release of histamine and other chemicals produces allergy symptoms.

Stages of an Allergic Reaction

White blood cells, or lymphocytes, are the body's watchdogs. Lymphocytes seek out, identify, and destroy possible threats to the body, called antigens. In other words, the lymphocytes are the warriors, and the antigens are the enemy.

Histamine can be released anywhere in the body

When a lymphocyte encounters an allergen, or allergy-causing substance, and mistakes it for a threat, it retreats to the lymph node, where it produces antibodies, or immunoglobulins, called IgE. Immunoglobulin is the body’s ammunition against the (perceived) enemy.

The body then begins to mass-produce IgE antibodies, which attach themselves to a type of white blood cell called a basophil. The immunogobulin also attaches to mast cells. Both basophils and mast cells contain histamine and other chemicals that cause allergy symptoms.

It takes time for the antibodies to build up in the body—a process called "sensitizing exposure." After a week to ten days, however, enough of IgE has built up that an "allergy cascade" occurs the next time the body encounters the antigen.

Source

An Allergy Cascade

Once the sensitizing exposure is completed, the body is primed to react the next time it encounters the allergen. The IgE antibodies that bound themselves to mast cells and basophils also bind themselves to the allergen proteins. As they do so, the antibodies set in motion a reaction designed to destroy the allergen. The attached mast cell or basophil is also destroyed, releasing its store of histamine.

Histamine can be released anywhere in the body, but is most often found in the skin, respiratory system or stomach. Different locations produce varying symptoms:

skin: hives and rashes
nose: sneezing, runny nose, and congestion
lungs: bronchial spasms and asthma symptoms
stomach: nausea, vomiting, and gastrointestinal upsets.

If histamine is released throughout the body, a life-threatening condition known as anaphylaxis may occur. Find out more about anaphylaxis and other symptoms on our
Allergic Reactions page.

Since one of the most common cores of allergy, asthma and sinusitis is fungal infections, as well as polyps, reflux disease and bacteria, you have to make sure that your home and real estate is free from molds and mildew, which later may develop into molds, and prevent any of their future growth.              

  • To eliminate molds and mildew from your home, office or other real estate and property, follow the suggestions of the book Do It Yourself Mold Prevention, Mold Inspection, Testing, & Remediation. For more info, please visit: Mold Book.

  • To visit the best internet mold website, please visit: Mold Inspector.

  • To find a Certified Mold Inspector, Certified Mold Remediator or Certified Mold Contractor in your area, please visit: Certified Mold Inspector.  

  • To find services of a mold lawyer or a mold attorney, please visit Mold Lawyer.

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The information provided on this website was obtained from sources believed to be accurate. The information is provided free as a public service with the specific understanding and agreement by the website visitor that the website publisher is not engaged in rendering medical or legal services. If medical or legal advice or assistance is required, the services of a competent, licensed medical doctor or attorney should be sought.


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